FLI
Vous trouverez dans cette rubrique les offres de stage, de thèses, de post doctorats, de CDD et CDI à pourvoir dans les laboratoires partenaires du réseau.
Liste des annonces
2016/08/26 Post-doctoral position in pre-clinical ultrasound and optical imaging, Paris
Our team in involved in the H2020 European Project Folsmart ( http://cordis.europa.eu/project/rcn/200186_en.html ) dedicated to the treatment of rheumatoid arthritis using a new strategy targeting folate receptors with a liposome-based nanovector. We are in charge of the pre-clinical evaluation of this nanovector and the investigation of its mechanism of action in mice. We will use in vivo imaging techniques to address these questions, including high resolution ultrasound, opto-acoustics (also called photoacoustics), in vivo bi-photon imaging and ultra-fast ultrasound imaging.
We offer a 2-year post-doctoral position to implement these tools in order to characterize and provide early assessment of the therapy in preclinical models of rheumatoid arthritis. Date of Employment should be between 17th October and the end of December 2016.
References:
Enhancing Methotrexate Tolerance with Folate Tagged Liposomes in Arthritic Mice. Nogueira E, Lager F, Le Roux D, Nogueira P, Freitas J, Charvet C, Renault G, Loureiro A, Almeida CR, Ohradanova-Repic A, Machacek C, Bernardes GJ, Moreira A, Stockinger H, Burnet M, Carmo AM, Gomes AC, Preto A, Bismuth G, Cavaco-Paulo A. J Biomed Nanotechnol. 2015 Dec;11(12):2243-52.
Ultrasound and Doppler micro-imaging in a model of rheumatoid arthritis in mice. Clavel G, Marchiol-Fournigault C, Renault G, Boissier MC, Fradelizi D, Bessis N. Ann Rheum Dis. 2008 Dec;67(12):1765-72.
Single-side access, isotropic resolution, and multispectral three-dimensional photoacoustic imaging with rotate-translate scanning of ultrasonic detector array. Gateau, J., Gesnik, M., Chassot, J.-M., & Bossy, E. (2015). Journal of Biomedical Optics, 20(5), 056004.
2016/08/26 Post-doctoral position in pre-clinical ultrasound and optical imaging, Paris
Our team in involved in the H2020 European Project Folsmart ( http://cordis.europa.eu/project/rcn/200186_en.html ) dedicated to the treatment of rheumatoid arthritis using a new strategy targeting folate receptors with a liposome-based nanovector. We are in charge of the pre-clinical evaluation of this nanovector and the investigation of its mechanism of action in mice. We will use in vivo imaging techniques to address these questions, including high resolution ultrasound, opto-acoustics (also called photoacoustics), in vivo bi-photon imaging and ultra-fast ultrasound imaging.
We offer a 2-year post-doctoral position to implement these tools in order to characterize and provide early assessment of the therapy in preclinical models of rheumatoid arthritis. Date of Employment should be between 17th October and the end of December 2016.
References:
Enhancing Methotrexate Tolerance with Folate Tagged Liposomes in Arthritic Mice. Nogueira E, Lager F, Le Roux D, Nogueira P, Freitas J, Charvet C, Renault G, Loureiro A, Almeida CR, Ohradanova-Repic A, Machacek C, Bernardes GJ, Moreira A, Stockinger H, Burnet M, Carmo AM, Gomes AC, Preto A, Bismuth G, Cavaco-Paulo A. J Biomed Nanotechnol. 2015 Dec;11(12):2243-52.
Ultrasound and Doppler micro-imaging in a model of rheumatoid arthritis in mice. Clavel G, Marchiol-Fournigault C, Renault G, Boissier MC, Fradelizi D, Bessis N. Ann Rheum Dis. 2008 Dec;67(12):1765-72.
Single-side access, isotropic resolution, and multispectral three-dimensional photoacoustic imaging with rotate-translate scanning of ultrasonic detector array. Gateau, J., Gesnik, M., Chassot, J.-M., & Bossy, E. (2015). Journal of Biomedical Optics, 20(5), 056004.
2016/04/26 Post-doctoral position in quantitative hepato-pancreatic MR imaging, Paris
The position involves the development, implementation and validation of MR acquisition and post-processing methods to obtain imaging biomarkers of chronic diseases and tumors in the liver and pancreas. Quantitative imaging studies will be performed in phantoms, liver and pancreatic tissue, small animals, and patients. The MR methods include perfusion and diffusion imaging, chemical shift encoded imaging, quantitative susceptibility mapping and MR elastography Advanced image analysis and data integration are part of our ongoing translational research program on quantitative MR imaging of liver and abdominal diseases.
The main purpose of our research team is the development of new imaging biomarkers in inflammation, fibrosis and cancer. Our translational research team is composed of medical doctors, researchers and engineers. The imaging research team is one of the 13 research teams of the Center of Research on Inflammation in Paris. It is part of the French National Institute for Medical Research (INSERM), the University of Paris Diderot, Sorbonne Paris Cité and is affiliated to the University Department of Gastroenterology and Hepatology (DHU Unity), as well as the French infrastructure for Imaging Research “France Life Imaging”.
The post-doctoral position has a 12-month initial employment basis, and may be renewable.
2016/04/26 Post-doctoral position in quantitative hepato-pancreatic MR imaging, Paris
The position involves the development, implementation and validation of MR acquisition and post-processing methods to obtain imaging biomarkers of chronic diseases and tumors in the liver and pancreas. Quantitative imaging studies will be performed in phantoms, liver and pancreatic tissue, small animals, and patients. The MR methods include perfusion and diffusion imaging, chemical shift encoded imaging, quantitative susceptibility mapping and MR elastography Advanced image analysis and data integration are part of our ongoing translational research program on quantitative MR imaging of liver and abdominal diseases.
The main purpose of our research team is the development of new imaging biomarkers in inflammation, fibrosis and cancer. Our translational research team is composed of medical doctors, researchers and engineers. The imaging research team is one of the 13 research teams of the Center of Research on Inflammation in Paris. It is part of the French National Institute for Medical Research (INSERM), the University of Paris Diderot, Sorbonne Paris Cité and is affiliated to the University Department of Gastroenterology and Hepatology (DHU Unity), as well as the French infrastructure for Imaging Research “France Life Imaging”.
The post-doctoral position has a 12-month initial employment basis, and may be renewable.
2016/03/03 Post-doctoral position – multimodal SEP data, Rennes, France
Early medullar MRI markers and late physical handicap in multiple sclerosis patients – Exploitation of a multimodal and multi-centric project database
The main goal of this post-doctoral position will be to develop and evaluate new methods for spinal cord MR analysis and derive markers of spinal cord burden related to ambulatory disability. Therefore, the work will encompass several methodological tasks starting with registration between different MR sequences and between different time points in the same subject, and between different subjects at a given time point. This work will, among others, rely on methods developed in the research team.
The second challenge will be devoted to the extraction of regions of interest in the spinal cord, whether white matter, gray matter, lesions or spinal cord tracts, using tools available from the literature or adapted from similar tasks on brain MRI for this purpose. The post-doctorate will further use all these tools to process the EMISEP database in order to evaluate both focal and diffuse burden as well as their evolution in time. The correlation between these markers and clinical scores acquired in parallel will then be investigated.
From a methodological perspective, this work will deal with
• registration between modalities, time points and patients
• segmentation of the spinal cord and MS lesions
• distortion correction
• statistical comparisons between imaging and clinical score
2016/03/03 CDI Développeur logiciel @ First Light Imaging
Localisé(e) à Meyreuil (Aix en Provence), le développeur logiciel aura pour missions
- L’écriture des Interfaces Hommes Machines de nos produits
- Participer au développement des softs embarqués.
- Développer les interfaces pour les suites logiciels de traitement d’images (Image J)
- Relayer l’ingénieur senior dans toutes ses missions.
Produit ultra innovant, marché mondial, environnement dynamique et porteur de réelles opportunités.
Véritable « codeur » il doit écrire et inventer les interfaces de nos produits à la pointe de la technologie mondiale du secteur.
Ingénieur grande école ayant une première expérience dans ce domaine, force de proposition pour améliorer et pérenniser l’existant.
Anglais opérationnel, le (la) candidat (e) idéal (e) est autonome et capable de travailler en équipe.
CDI, salaire selon profil.
2016/03/03 CDI Développeur logiciel @ First Light Imaging
Localisé(e) à Meyreuil (Aix en Provence), le développeur logiciel aura pour missions
- L’écriture des Interfaces Hommes Machines de nos produits
- Participer au développement des softs embarqués.
- Développer les interfaces pour les suites logiciels de traitement d’images (Image J)
- Relayer l’ingénieur senior dans toutes ses missions.
Produit ultra innovant, marché mondial, environnement dynamique et porteur de réelles opportunités.
Véritable « codeur » il doit écrire et inventer les interfaces de nos produits à la pointe de la technologie mondiale du secteur.
Ingénieur grande école ayant une première expérience dans ce domaine, force de proposition pour améliorer et pérenniser l’existant.
Anglais opérationnel, le (la) candidat (e) idéal (e) est autonome et capable de travailler en équipe.
CDI, salaire selon profil.
2016-02-22 Postdoctoral position : Methodological developments in diffusion MRI, Bordeaux, France
A 18-month postdoctoral position is available under the supervision of Dr. Bassem HIBA at the university of Bordeaux, France. The position will consist in developing new high challenging methods for high resolution diffusion MRI. Developments will include MR image reconstruction using the Gadgetron library as well as pulse sequence programming. The candidate will work in a multidisciplinary team including physicists, computer and MRI scientists with a collaboration with SIEMENS.
Facilities:
The team has access to two research human MRI scanners (3T, PRISMA, SIEMENS).
Environment:
Bordeaux is a 1-million urban area and hosts one of the largest university and research community in France. It is located in the South west of France in close proximity of the Atlantic Ocean. The city, part of the World Heritage List, offers a wide range of cultural and outdoors activities.
Conditions of employment
The duration of the position is 18 months. The gross annual salary is of 48 000 € with support from the “Bordeaux Idex”.
For more information and application please contact:
Bassem HIBA Ph.D
Senior researcher, CNRS
UMR 5287-Institut de Neurosciences Cognitives et Intégratives d'Aquitaine
Université de Bordeaux
Zone nord Bat 2 ème étage
146, rue Léo Saignat
33076 Bordeaux cedex. France
Tel: +33 5 57 57 17 34
email: bassem.hiba[at]u-bordeaux.fr
2016-02-22 Postdoctoral position : Methodological developments in diffusion MRI, Bordeaux, France
A 18-month postdoctoral position is available under the supervision of Dr. Bassem HIBA at the university of Bordeaux, France. The position will consist in developing new high challenging methods for high resolution diffusion MRI. Developments will include MR image reconstruction using the Gadgetron library as well as pulse sequence programming. The candidate will work in a multidisciplinary team including physicists, computer and MRI scientists with a collaboration with SIEMENS.
Facilities:
The team has access to two research human MRI scanners (3T, PRISMA, SIEMENS).
Environment:
Bordeaux is a 1-million urban area and hosts one of the largest university and research community in France. It is located in the South west of France in close proximity of the Atlantic Ocean. The city, part of the World Heritage List, offers a wide range of cultural and outdoors activities.
Conditions of employment
The duration of the position is 18 months. The gross annual salary is of 48 000 € with support from the “Bordeaux Idex”.
For more information and application please contact:
Bassem HIBA Ph.D
Senior researcher, CNRS
UMR 5287-Institut de Neurosciences Cognitives et Intégratives d'Aquitaine
Université de Bordeaux
Zone nord Bat 2 ème étage
146, rue Léo Saignat
33076 Bordeaux cedex. France
Tel: +33 5 57 57 17 34
email: bassem.hiba[at]u-bordeaux.fr
2016-02-22 Research fellow in theoretical/computational neuroscience
Open position: Research fellow in theoretical/computational neuroscience
Project title: Function brain tractography (F-TRACT)
Funding body: European Research Council (ERC)
Host institution: Inserm
Contract duration: 1 year, renewable
Starting date: As soon as possible. Applications will be considered until the position is filled.
Job description:
The successful candidate will have to develop the theoretical part of the F-TRACT project, which mainly aims at developing large-scale hierarchal brain model(s) using new information produced by the F-TRACT atlas. The model(s) developed will need to be directly connected to the F-TRACT data.
Project scientific summary:
In patients suffering from focal drug-resistant epilepsy who are explored using intracranial electrodes, single-pulse direct electrical stimulation of a cortical region induces electrophysiological responses in many of the implanted electrodes. The presence, latency and morphological characteristics of these cortico-cortical induced potentials can be used to infer functional and anatomical brain connectivity.
Intracerebral electrodes record from a small fraction of the volume of the brain in a single individual, allowing studying only a small fraction of the possible brain connections.
In F-TRACT, we develop methods to analyse those responses in order to create a new probabilistic atlas of electrophysiological functional tractography of the human brain, which will be made freely available to the clinical and neuroscience community. Several thousand stimulation runs performed in several hundred patients will be included in the atlas database to reach a nearly full coverage of the
human cortex. Neuroanatomical data (MRI, CT), electrophysiological data (intracranial EEG) and clinical data (e.g. epilepsy type, age at surgery, anatomical lesion, epileptogenic region) are confidentially gathered by the F-TRACT project from epilepsy surgery centres worldwide.
This new atlas of functional tractography will be very useful to understand how the brain works and to develop neurocomputational models at a large scale. It will also allow the development of new clinical tools for the presurgical evaluation of intractable epilepsy.