Grand Est


Coordinator: Jacques Felblinger

Project manager: Barbara Fischer

Local administrative coordination: University of Lorraine (Université de Lorraine UL) & University of Strasbourg (Université de Strasbourg UNISTRA)



FLI’s Grand Est hub is one of three hubs integrated into the infrastructure on June 1, 2020.

It is composed of five main imaging platforms with in vivo imaging modalities open to the research community:











Open to academic and industrial partnership research, the Grand Est hub covers the spectrum of in vivo imaging modalities (MRI, Nuclear, Optical and Ultrasound for human and animal applications). The hub has strong skills in instrumentation, in diagnostic and interventional imaging as well as in robotics. The Grand Est hub research laboratories (LORIA-INRIA, CRAN, ICube, IPHC and IADI) offer a large competence in data management, image processing and 3D navigation.

In addition, there is recognized expertise in the radiolabelling of molecules for molecular imaging associated with the production of short-long half-life positron emitting radioisotopes for diagnostic and theranostic applications and in proton beam irradiation.

Main expertise

The Grand Est hub expertise spans very broad fields:

  • Functional MRI and real-time image reconstruction, movement tracking,
  • Vocal tract imaging,
  • Vascular modeling and modeling of deformable organs for interventional procedures,
  • 3D navigation in images for guided interventions,
  • Nanobiophotonics and multifunctional nanoparticles,
  • Large field, quantitative, real time, fluorescence and microscopic optical imaging,
  • Intraoperative Multimodal and multispectral optical imaging (fluorescence, absorption and scattering), modelling of light interactions with biological tissues and experimental characterization of biological tissues optical properties (quantification and mapping),
  • X imaging, bioluminescence and tomography,
  • HiFUs, interventional imaging and thermal therapies,
  • Development of molecules labelled with positron emitters for molecular imaging,
  • Image and data processing: 2D and 3D registration, segmentation, reconstruction, 3D navigation, features extraction, classification,
  • Brain imaging.


Imaging platforms


Research laboratories associated to the platforms

  • The Diagnosis and International Adaptive Imaging laboratory: IADI, INSERM U1254 in Nancy,
  • The “Centre de Recherche en Automatique de Nancy”: CRAN, UMR 7039 in Nancy,
  • Nancyclotep in Nancy,
  • The Lorraine Research Laboratory in Computer Science and its Applications: LORIA, UMR 7503 in Nancy,
  • The Engineering science, computer science and imaging laboratory: ICube, UMR 7357 in Strasbourg,
  • The Radiobiology, Hadrontherapy et Molecular Imaging Department: DRHIM at IPHC in Strasbourg.